July 14, 2020

Liver Injury in Critically Ill and Non-Critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• Results from a retrospective observational study (n=131) across three hospitals in Zhejiang, China suggest that critically ill COVID-19 patients suffered earlier occurrence, greater injury severity, and slower recovery from liver injury compared to non-critically ill patients. The combination treatment of lopinavir/ritonavir and arbidol was associated with higher risk or liver injury among non-critically ill patients (OR=3.58, 95%CI: 1.44-9.52). 

Jiang et al. (June 23, 2020). Liver Injury in Critically Ill and Non-Critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study. Frontiers in Medicine. https://doi.org/10.3389/fmed.2020.00347