July 15, 2020

Comparison of Mortality Risk in Patients with Cirrhosis and COVID-19 Compared with Patients with Cirrhosis Alone and COVID-19 Alone: Multicentre Matched Cohort

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

• A multicenter study in the US compared 37 inpatients with cirrhosis and COVID-19 to age– and gender-matched patients with COVID-19 alone (n=108) or cirrhosis alone (n=127). Results showed that patients with cirrhosis and COVID-19 had a non-significantly higher mortality compared to patients with cirrhosis alone (30% vs 20%, p=0.16), and significantly higher mortality than patients with COVID-19 alone (30% vs 13%, p=0.03). The elevated mortality among those with cirrhosis and COVID-19 may be at least partially attributable to a higher degree of co-morbidities, as measured by the Charlson Comorbidity Index. 

Bajaj et al. (July 13, 2020). Comparison of Mortality Risk in Patients with Cirrhosis and COVID-19 Compared with Patients with Cirrhosis Alone and COVID-19 Alone: Multicentre Matched Cohort. Gut. https://doi.org/10.1136/gutjnl-2020-322118