Alliance for Pandemic Preparedness

July 15, 2020

SARS-CoV-2 Antibody Responses Do Not Predict COVID-19 Disease Severity

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  • Based on a sample of 172 suspected cases of SARS-CoV-2 and 795 negative plasma samples, IgG antibody testing had a 100% specificity (0/795) and IgG tests were positive for 83% of suspected cases among samples collected more than 14 days from symptom onset.  
  • There was no association between the level of IgG and IgM reactivity and mild versus severe disease course. 

Phipps et al. (July 15, 2020). SARS-CoV-2 Antibody Responses Do Not Predict COVID-19 Disease Severity. American Journal of Clinical Pathology. https://doi.org/10.1093/ajcp/aqaa123