Alliance for Pandemic Preparedness

July 15, 2020

Transplacental Transmission of SARS-CoV-2 Infection

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  • Vivanti et al. demonstrated a transplacental transmission of SARS-CoV-2 in a neonate born to a mother infected in the third trimester and delivered at the Paris Saclay University Hospitals. RT-PCR testing for SARS-CoV-2 was positive from multiple sites from the neonate, including blood, bronchoalveolar lavage fluid, nasopharyngeal and rectal swabs, and placental samples. The neonate presented with neurological manifestations, similar to those described in adult patients. 

Vivanti et al. (Dec 14, 2020). Transplacental Transmission of SARS-CoV-2 Infection. Nature Communications. https://doi.org/10.1038/s41467-020-17436-6