Alliance for Pandemic Preparedness

July 16, 2020

Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US

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  • In a US multicenter cohort study of COVID-19 patients admitted to ICU (n=2,215), independent risk factors associated with 28 day mortality included older age (≥80 vs <40 years of age: OR=11.15), male sex (OR=1.50), obesity (BMI ≥40 vs <25: OR=1.51), coronary artery disease (OR=1.47), active cancer (OR=2.15), and acute organ dysfunction (OR=2.43 to 2.61). Patients admitted to a hospital with fewer ICU beds had a higher risk of death (<50 vs ≥100 ICU beds: OR=3.28). Overall, 35% of the cohort died within 28 days. 

Gupta et al. (July 15, 2020). Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2020.3596