Alliance for Pandemic Preparedness

July 17, 2020

Vascular Risk Factors, Framingham Risk Score, and COVID-19: Community-Based Cohort Study

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  • A community-based prospective cohort study using UK Biobank data found that current smoking, physical inactivity, obesity/overweight, and diabetes were all positively associated with SARS-CoV-2 risk (adjusted for age, sex, alcohol intake, education, and ethnicity, and other CVD risk factors). There was no evidence of association for systolic blood pressure. Total cholesterol and HDL were associated with lower risk. Framingham risk score was positively associated with SARS-CoV-2 in the two highest quintiles, but not at intermediate or lower values. 

Batty and Hamer. (July 16, 2020). Vascular Risk Factors, Framingham Risk Score, and COVID-19: Community-Based Cohort Study. Cardiovascular Research. https://doi.org/10.1093/cvr/cvaa178