July 20, 2020

Going beyond Clinical Routine in SARS-CoV-2 Antibody Testing – A Multiplex Corona Virus Antibody Test for the Evaluation of Cross-Reactivity to Endemic Coronavirus Antigens

Category: Article Summary

Topic: Testing and Treatment

• [pre-print, not peer-reviewed] Becker et al. developed a multiplexed immunoassay to measure IgG and IgA responses against six SARS-CoV-2 antigens, achieving a sensitivity of 90% and a specificity of 100%. By monitoring IgA response, they were able to detect an early immune response in some patients. The authors suggest that the test may be useful in monitoring vaccination studies and conducting widespread screening.  

Becker et al. (July 17, 2020). Going beyond Clinical Routine in SARS-CoV-2 Antibody Testing – A Multiplex Corona Virus Antibody Test for the Evaluation of Cross-Reactivity to Endemic Coronavirus Antigens. Pre-print downloaded July 20 from https://doi.org/10.1101/2020.07.17.20156000