Alliance for Pandemic Preparedness

July 27, 2020

Point-of-Care Serological Assays for Delayed SARS-CoV-2 Case Identification among Health-Care Workers in the UK: A Prospective Multicentre Cohort Study

Category:

Topic:

  • A multicenter cohort study based in the UK found that lateral flow point-of-care and ELISA tests for SARS-CoV-2 antibodies had good positive and negative predictive values when conducted among a carefully selected population with suspected SARS-CoV-2 infection. The authors conclude that these test have potential for late case identification among healthcare workers with mild to moderate SARS-CoV-2 infection, but also discuss important limitations, including late development of bands on lateral flow assays that may limit their application. 

Pallett et al. (July 24, 2020). Point-of-Care Serological Assays for Delayed SARS-CoV-2 Case Identification among Health-Care Workers in the UK: A Prospective Multicentre Cohort Study. The Lancet Respiratory Medicine. https://doi.org/10.1016/S2213-2600(20)30315-5