Alliance for Pandemic Preparedness

July 28, 2020

A Prospective Cohort Study in Non-Hospitalized Household Contacts with SARS-CoV-2 Infection: Symptom Profiles and Symptom Change over Time

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  • Out of 198 household contacts exposed to SARS-CoV-2 in Wisconsin and Utah and followed longitudinally (PCR two or more times during a 14 day period) from March 22 to April 22, 47 were positive by PCR, representing an attack rate of 24%. Among children under 18 years, the attack rate was 20%, versus 26% for adults 18 years or older. While symptom distribution varied by age, upper respiratory (68%) and neurological (64%) symptoms were the most common, while fever was not commonly reported (19%).  

Yousaf et al. (July 2020). A Prospective Cohort Study in Non-Hospitalized Household Contacts with SARS-CoV-2 Infection: Symptom Profiles and Symptom Change over Time. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1072