Alliance for Pandemic Preparedness

July 29, 2020

Relationship Between Serum SARS-CoV-2 Nucleic Acid (RNAemia) and Organ Damage in COVID-19 Patients: A Cohort Study

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  • Among a cohort of 85 COVID-19 patients hospitalized with laboratory-confirmed COVID-19 in Wuhan, China, 32 had SARS-CoV-2 RNA detected in serum (RNAemia). Compared to patients without RNAemia, patients with RNAemia had higher rate of organ damage (18/32 [56%] vs. 5/53 [9%], p<0.001), higher mortality (10/32 [31%] vs. 3/53 [6%], p=0.004), , and a variety of abnormal CT and laboratory biomarkers. 

Xu et al. (July 28, 2020). Relationship Between Serum SARS-CoV-2 Nucleic Acid (RNAemia) and Organ Damage in COVID-19 Patients: A Cohort Study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1085