July 31, 2020

ChAdOx1 NCoV-19 Vaccine Prevents SARS-CoV-2 Pneumonia in Rhesus Macaques

Category: Article Summary

Topic: Vaccines and Immunity

• A single dose of a vaccine similar to one previously discovered to protect against MERS was reported by van Doremalen et al. to produce neutralizing antibodies specific to SARS-CoV-2 in both mice and rhesus macaques. A booster shot significantly improved humoral immune response in macaques. The vaccine candidate is moving on to clinical trials.  

van Doremalen et al. (July 30, 2020). ChAdOx1 NCoV-19 Vaccine Prevents SARS-CoV-2 Pneumonia in Rhesus Macaques. Nature. https://doi.org/10.1038/s41586-020-2608-y