August 18, 2020

SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness

Category: Article Summary

Topic: Testing and Treatment

• [Pre-print, not peer reviewed] Severely ill patients developed significantly higher SARS-CoV-2 specific antibody responses, based on analysis of 625 serial plasma samples from 40 hospitalized patients with COVID-19 and 170 SARS-CoV-2 infected outpatients and asymptomatic individuals. The development of plasma antibodies was also correlated with decreases in viral RNAemia, suggesting potential humoral immune clearance of virus. Additionally, the serological responses of outpatient and asymptomatic individuals were found to decrease within 2 months. 

Röltgen et al. (Aug 17, 2020). SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness. Pre-print downloaded Aug 18 from https://doi.org/10.1101/2020.08.15.20175794