Alliance for Pandemic Preparedness

August 19, 2020

SARS-CoV-2 (COVID-19) Infection in Pregnant Women Characterization of Symptoms and Syndromes Predictive of Disease and Severity through Real-Time Remote Participatory Epidemiology

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  • [Pre-print, not peer reviewed] An observational study used a smartphone application and web-based survey to collect self-reported pregnancy status and COVID-19-related symptom information from >400,000 women in the UK and Sweden and >1.3 million reports from women in the US. Investigators found that the profile of SARS-CoV-2 symptom characteristics and severity among pregnant women were comparable to those observed among non-pregnant women, except for gastrointestinal symptoms. Pregnant women were more likely to have received SARS-CoV-2 testing than non-pregnant women, despite reporting fewer clinical symptoms. Consistent with observations in non-pregnant populations, comorbidities such as lung disease and diabetes were associated with an increased risk of more severe SARS-CoV-2 infection during pregnancy.  

Molteni et al. (Aug 19, 2020). SARS-CoV-2 (COVID-19) Infection in Pregnant Women Characterization of Symptoms and Syndromes Predictive of Disease and Severity through Real-Time Remote Participatory Epidemiology. Pre-print downloaded Aug 19 from https://doi.org/10.1101/2020.08.17.20161760