August 21, 2020

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): treatment

• An open-label randomized trial of 5- or 10-days of remdesivir treatment compared to standard care found that 5-day remdesivir treatment had a statistically significant improvement in clinical status on day 11 after initiation of treatment, although the clinical importance of the effect was uncertain. The difference in clinical status on day 11 between the 10-day remdesivir and standard care groups was not significantly different (P = 0.18).

Spinner et al. (Aug 21, 2020). Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial. JAMA. https://doi.org/10.1001/jama.2020.16349