August 25, 2020

Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• Preliminary findings from a cohort study of 192 children (mean age 10.2 +/- 7 years) hospitalized with COVID-19 in Massachusetts show that among participants with acute SARS-CoV-2 infection (n=49) viral load in respiratory secretions in the first 2 days of symptoms was significantly higher compared to that of hospitalized adults with severe disease and more than 7 days of symptoms. There was substantial overlap in symptoms between children with SARS-CoV-2 infection, multi-system inflammatory syndrome, and SARS-CoV-2 suspected children who tested negative.

Yonker et al. (Aug 18, 2020). Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses. The Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2020.08.037