Alliance for Pandemic Preparedness

August 27, 2020

Clinical Features of Neonates Born to Mothers with Coronavirus Disease-2019: A Systematic Review of 105 Neonates

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  • A systematic review of 14 studies involving 105 neonates born to mothers with COVID-19 found that most had favorable outcomes. Overall, 25 infants (24%) were delivered preterm, 10 (11%) were small for gestational age (SGA), and 28 (27%) had COVID-19 symptoms. Among 91 neonates who were tested for SARS-CoV-2, 8 (9%) were positive. COVID-19 symptoms after birth were more common among those who tested SARS-CoV-2 positive (5/8, 63%) compared to those who were negative (17/83, 21%). There were no significant differences in SGA, preterm delivery, duration between maternal symptom onset and delivery, or perinatal complication based on SARS-CoV-2 test results.

Chi et al. (Aug 14, 2020). Clinical Features of Neonates Born to Mothers with Coronavirus Disease-2019: A Systematic Review of 105 Neonates. Journal of Microbiology, Immunology, and Infection. https://doi.org/10.1016/j.jmii.2020.07.024