August 31, 2020

Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): immune, treatment

• Severe adverse events related to transfusion of convalescent plasma were rare (<1%) among a sample of 20,000 adult patients with severe or life-threatening lab-confirmed COVID-19 who received convalescent plasma treatment. A total of 141(<1%) people experienced serious adverse events (SAEs) related to the transfusion of convalescent plasma within four hours of the procedure and an additional 1,247 (6%) SAEs were reported within seven days of transfusion.

Joyner et al. (Sept 2020). Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients. Mayo Clinic Proceedings. https://pubmed.ncbi.nlm.nih.gov/32861333/