Alliance for Pandemic Preparedness

September 4, 2020

Risk Factors for COVID-19 Death in a Population Cohort Study from the Western Cape Province, South Africa

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  • HIV and tuberculosis were each associated with increased risk of COVID-19 mortality in a population cohort study in South Africa (n=3,460,932) that included 625 deaths due to COVID-19. In models adjusted for age, sex, and comorbidities, the HIV-associated risk was 2.1 (95% CI 1.7-2.7), compared to 2.7 (95% CI 1.8-4.0) for current tuberculosis and 1.5 (95% CI 1.2-1.9) for prior tuberculosis. The models adjusted for location of residence, but did not have data available to adjust for other measures of socioeconomic status that may be associated with HIV and TB.

Boulle et al. (2020). Risk Factors for COVID-19 Death in a Population Cohort Study from the Western Cape Province, South Africa. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1198