Alliance for Pandemic Preparedness

September 10, 2020

Clinical Characteristics and Outcomes of Immunosuppressed Patients Hospitalized with COVID-19: Experience from London

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• In a cohort study of 981 confirmed COVID-19 patients consecutively hospitalized at a large North West London hospital between March 12 and April 15, taking high dose immunosuppressive medications, such as for autoimmune disease or solid organ transplant, was associated with significantly higher mortality rates, supporting the current UK government’s early isolation (“shielding”) policy for these individuals. During the follow-up period, 36% of study patients died. The immunosuppressed cohort (n=31) had significantly higher mortality rates (aHR=2.1, 95%CI 1.2-3.6).

Vaid et al. (Sept 9, 2020). Clinical Characteristics and Outcomes of Immunosuppressed Patients Hospitalized with COVID-19: Experience from London. Journal of Internal Medicine. https://pubmed.ncbi.nlm.nih.gov/32902028