September 10, 2020

High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): immunity, testing

• Among asymptomatic residents of Chelsea, Massachusetts without a prior positive PCR test for SARS-CoV-2 (n=200), the seroprevalence of SARS-CoV-2 antibodies was 32% (18% IgM+IgG+, 9% IgM+IgG-, and 5% IgM-IgG+), representing a substantial burden of undocumented infection. Additionally, 51% of participants reported no symptoms in the preceding 4 weeks, of whom 25% (25/101) were seropositive, and 60% of these were IgM+IgG-.

Naranbhai et al. (Sept 9, 2020). High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiaa579