September 11, 2020

Elevated D-Dimers and Lack of Anticoagulation Predict PE in Severe COVID-19 Patients

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• Pulmonary embolism (PE) was diagnosed in 44/162 (27%) patients hospitalized with COVID-19 in a university hospital in France who had severe respiratory disease or rapid clinical worsening and who received computed tomography pulmonary angiography. Elevated D-dimer level (OR=4.0 per additional quartile) and lack of anticoagulant therapy (OR=4.5) were associated with confirmed PE. D-dimer level >2590 ng/mL was associated with a 17-fold increase in the adjusted risk of PE.

  Mouhat et al. (Sept 9, 2020). Elevated D-Dimers and Lack of Anticoagulation Predict PE in Severe COVID-19 Patients. The European Respiratory Journal. https://doi.org/10.1183/13993003.01811-2020