September 18, 2020

Evaluation of Performance of Two SARS-CoV-2 Rapid IgM-IgG Combined Antibody Tests on Capillary Whole Blood Samples from the Fingertip

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): testing

• Two point-of-care serology tests utilizing capillary whole blood samples from a finger prick (COVID-PRESTO and COVID-DUO) had 100% sensitivity and 100% specificity for SARS-CoV-2 antibodies when administered at least 15 days after symptom onset. Sensitivity was calculated among patients who tested positive by PCR (n=238) and specificity was calculated among patients negative by PCR (n=143). Sensitivity was only 10% within five days of symptom onset.

Prazuck et al. (Sept 17, 2020). Evaluation of Performance of Two SARS-CoV-2 Rapid IgM-IgG Combined Antibody Tests on Capillary Whole Blood Samples from the Fingertip. PLOS ONE. https://doi.org/10.1371/journal.pone.0237694