September 18, 2020

Recovered COVID-19 Patients with Recurrent Viral RNA Exhibit Lower Levels of Anti-RBD Antibodies

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• Patients who recovered from COVID-19 (n=47) and had a recurrent positive SARS-CoV-2 RNA test had significantly lower levels of anti-receptor binding domain (RBD) IgG antibodies than persistently RNA-negative patients (p=0.013). The authors conclude that this suggests that anti-RBD IgG levels could predict recovered patients who are at risk of viral rebound.

Liu et al. (Sept 16, 2020). Recovered COVID-19 Patients with Recurrent Viral RNA Exhibit Lower Levels of Anti-RBD Antibodies. Cellular & Molecular Immunology. https://doi.org/10.1038/s41423-020-00528-0