Alliance for Pandemic Preparedness

September 22, 2020

COVID-19 Herd Immunity in the Brazilian Amazon



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  • [Pre-print, not peer-reviewed] Between 44% and 66% of the population of Manaus, Brazil was infected with SARS-CoV-2 through the course of the epidemic, as estimated by a study of cross-sectional monthly seroprevalence estimates in blood donors. According to Buss et al., although nonpharmaceutical interventions and other changes in population behavior may have helped to limit SARS-CoV-2 transmission in Manaus, the unusually high infection rate suggests that herd immunity may have played a role in determining the size of the epidemic.

Buss et al. (Sept 21, 2020). COVID-19 Herd Immunity in the Brazilian Amazon. Pre-print downloaded Sept 22 from