Alliance for Pandemic Preparedness

September 30, 2020

The Role of Anti-Hypertensive Treatment, Comorbidities and Early Introduction of LMWH in the Setting of COVID-19: A Retrospective, Observational Study in Northern Italy

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  • Chronic treatment with the antihypertensive medications angiotensin converting enzyme inhibitors (ACE-I) and early treatment with low-molecular-weight heparin (LMWH) were both associated with lower in-hospital mortality in a cohort of patients hospitalized with COVID-19 in Italy (n=575), after adjusting for age. Angiotensin receptor blockers, which are also antihypertensive agents acting on the same physiological pathway, were not associated with differences in mortality.

Desai et al. (Sept 24, 2020). The Role of Anti-Hypertensive Treatment, Comorbidities and Early Introduction of LMWH in the Setting of COVID-19: A Retrospective, Observational Study in Northern Italy. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2020.09.062