October 2, 2020

Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March – August 2020

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• Morris et al. report 27 cases of multisystem inflammatory syndrome (MIS) associated with SARS-CoV-2 infection in adults that have been reported to CDC or published in the literature. MIS has been previously described among children and adolescents. MIS differs from typical manifestations of severe COVID-19 in that patients with MIS have minimal respiratory symptoms, hypoxemia, or radiographic abnormalities. The interval between infection and development of MIS in adults is unclear, adding to uncertainty regarding whether MIS in adults represents a manifestation of acute infection or a different, post-acute phenomenon. Antibody testing was required to identify SARS-CoV-2 infection in 9 of the 27 individuals.

Morris et al. (2020). Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March – August 2020. http://dx.doi.org/10.15585/mmwr.mm6940e1