October 2, 2020

Waning of SARS-CoV-2 RBD Antibodies in Longitudinal Convalescent Plasma Samples within Four Months after Symptom Onset

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

• A decrease in anti-RBD antibodies was observed over time in a study of individuals who had recovered from SARS-CoV-2 and who gave repeated blood donations. The study determined that the decline was not due to repeated donations, but rather that the anti-RBD response wanes over time of convalescence. The response was found to be relatively stable over the first 10 weeks after disease onset.

Perreault et al. (Oct 2020). Waning of SARS-CoV-2 RBD Antibodies in Longitudinal Convalescent Plasma Samples within Four Months after Symptom Onset. Blood. https://pubmed.ncbi.nlm.nih.gov/33001206