October 15, 2020

Healthcare Workers with Mild Asymptomatic SARS-CoV-2 Infection Show T Cell Responses and Neutralising Antibodies after the First Wave

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): immunity

• [Pre-print, not peer reviewed] A cohort study of 136 healthcare workers in the UK found that 90% of the 76 workers with mild or asymptomatic SARS-CoV-2 infection had detectable neutralizing antibodies at the beginning of the lockdown and 66% of the same workers had them after 16-18 weeks. T-cell responses tended to be lower among asymptomatic participants, while neutralizing antibody titers were maintained irrespective of symptoms, suggesting that healthcare workers may retain some functional protection for at least 4 months after experiencing mild or asymptomatic infection.

Reynolds et al. (Oct 14, 2020). Healthcare Workers with Mild Asymptomatic SARS-CoV-2 Infection Show T Cell Responses and Neutralising Antibodies after the First Wave. Pre-print downloaded Oct 15 from https://doi.org/10.1101/2020.10.13.20211763