October 21, 2020

Seroprevalence of Anti‐SARS‐CoV‐2 Antibodies in COVID‐19 Patients and Healthy Volunteers up to Six Months Post Disease Onset

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): antibodies, immunity

A study among patients who tested positive for SARS-CoV-2 by PCR reported an increase in the detection of antibodies against the SARS-CoV-2 receptor binding domain (RBD) and spike protein using ELISA rapidly during the acute phase after infection, with a peak in detection around week 3. The detection of IgG antibodies remained robust, with confirmed neutralization activity for up to six months. The study cohort included 307 COVID-19 hospital patients and healthcare workers at a central hospital, 38 staff members at the University of Lisbon who were tested positive during the mass screening, and 198 plasma donors who registered voluntarily online in Portugal. 

Figueiredo‐Campos et al. (Oct 21, 2020). Seroprevalence of Anti‐SARS‐CoV‐2 Antibodies in COVID‐19 Patients and Healthy Volunteers up to Six Months Post Disease Onset. European Journal of Immunology. https://doi.org/10.1002/eji.202048970