October 28, 2020

Declining Prevalence of Antibody Positivity to SARS-CoV-2 a Community Study of 365000 Adults

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): antibodies

[Pre-print, not peer reviewed] Results from 3 non-overlapping cohorts in the UK demonstrated that the overall prevalence of detectable IgG antibodies against SARS-CoV-2 declined by 27% (from 6.0% to 4.4%) between late June and September 2020. Greater levels of decline were seen among older people aged 75+ years (-39%) compared to those 18-24 years old (-15%) and people who did not report a history of COVID-19 symptoms (-64%) compared to those with SARS-CoV-2 infection confirmed on PCR (-22%). 

Ward et al. (Oct 27, 2020). Declining Prevalence of Antibody Positivity to SARS-CoV-2 a Community Study of 365000 Adults. Pre-print downloaded Oct 28 from https://doi.org/10.1101/2020.10.26.20219725