October 28, 2020

High Seroprevalence but Short-Lived Immune Response to SARS-CoV-2 Infection in Paris

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

[Pre-print, not peer reviewed] In a cohort of workers outside Paris, both the concentration (titer) and quality of antibodies against SARS-CoV-2 declined 4-8 weeks after sampling. Among a cohort of 1,847 active workers in the Paris conurbation in France, 11% were positive for IgG against SARS-CoV-2-specific protein and 9.5% had evidence of viral neutralization. After 4-8 weeks since the first sampling, anti-N and anti-S IgG titers and neutralization activity declined by 31%, 17%, and 53%, respectively.

Anna et al. (Oct 27, 2020). High Seroprevalence but Short-Lived Immune Response to SARS-CoV-2 Infection in Paris. Pre-print downloaded Oct 28 from https://doi.org/10.1101/2020.10.25.20219030