October 29, 2020

Robust Neutralizing Antibodies to SARS-CoV-2 Infection Persist for Months

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

• Analysis of a serology dataset from patients admitted to a New York City hospital with confirmed or suspected SARS-CoV-2 infection (n=30,082) showed that the vast majority of individuals (~92%) had moderate-to-high titers (> 1:320) of anti-spike antibodies with 90% of seroconverters making detectable neutralizing antibodies. Additionally, antibody titers from a cohort of 121 plasma donors were found to be stable over at least 3 months, with modest declines at 5 months.

Wajnberg et al. (Oct 28, 2020). Robust Neutralizing Antibodies to SARS-CoV-2 Infection Persist for Months. Science. https://doi.org/10.1126/science.abd7728