October 30, 2020

Case Fatality Rates for COVID-19 Patients Requiring Invasive Mechanical Ventilation: A Meta-Analysis

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• A meta-analysis of the case fatality ratio among adults with COVID-19 receiving invasive mechanical ventilation (IMV) indicated that the estimated case fatality ratio was 45% (95% CI 39-52%). Among studies where age-specific case fatality ratios were available, pooled estimates ranged from 48% in younger patients (age ≤40) to 84% in older patients (age >80). Case fatality ratios were also higher in early epicenters. The authors note that overall heterogeneity was high and that variable reporting methods resulted in a wide range of estimates between studies.

Lim et al. (Oct 29, 2020). Case Fatality Rates for COVID-19 Patients Requiring Invasive Mechanical Ventilation: A Meta-Analysis. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.202006-2405OC