Alliance for Pandemic Preparedness

November 4, 2020

Association of COVID-19 RT-QPCR Test False-Negative Rate with Patient Age Sex and Time since Diagnosis

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[Preprint, not peer-reviewed] A study using electronic health records in Israel reported that the 11% of PCR tests for SARS-CoV-2 were negative with 0-5 days of clinical diagnosis among patients who had at least one positive PCR test (n= 521,696). Patients who were female (vs. male: OR=1.7) and patients who were younger (10 vs. 40 years of age: OR=2.5) were more likely to have a false-negative result.

Levine-Tiefenbrun et al. (Nov 3, 2020). Association of COVID-19 RT-QPCR Test False-Negative Rate with Patient Age Sex and Time since Diagnosis. Pre-print downloaded Nov 4 from https://doi.org/10.1101/2020.10.30.20222935