November 12, 2020

Large Scale Genomic Analysis of 3067 SARS-CoV-2 Genomes Reveals a Clonal Geo-Distribution and a Rich Genetic Variations of Hotspots Mutations

Category: Article Summary

Topic: Geographic Spread

Keywords (Tags): genomics, geographic spread

• A large-scale analysis of 3067 SARS-CoV-2 genomes from 55 countries tracked mutations within the virus genome and identified three major clades in various geographic regions. The analysis also revealed geographic mutation hotspots – in particular, China, the US, France, and Malaysia – contained a high number of specific mutations. The authors note the high number of mutations may be the cause of rapid transmission in the US and may be associated with the severity of the epidemic in the US and France.

Laamarti et al. (Nov 10, 2020). Large Scale Genomic Analysis of 3067 SARS-CoV-2 Genomes Reveals a Clonal Geo-Distribution and a Rich Genetic Variations of Hotspots Mutations. PLOS ONE. https://doi.org/10.1371/journal.pone.0240345