November 12, 2020

Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

• Analysis of longitudinal antibody responses of 76 COVID-19 patients followed for approximately 100 days showed that while anti-spike protein IgG levels declined rapidly for most individuals, those with sustained (and in some instances increased) anti-spike protein IgG levels experienced shorter disease course (median 10 vs. 16 days). Being an antibody “sustainer” also predicted persistent neutralizing antibody responses up to 145 days post-symptom onset.

Chen et al. (Nov 3, 2020). Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production. Cell. https://doi.org/10.1016/j.cell.2020.10.051