November 19, 2020

SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): clinical characteristics

• A study evaluating novel ELISA-based assays to detect SARS-CoV-2 antibodies (including antibody sandwich ELISA and three isotype-specific assays) found that among convalescent patients (n=350), IgM, IgA, and IgG antibody responses against the receptor-binding domain significantly correlated with disease severity.

Hansen et al. (Nov 18, 2020). SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals. The Journal of Immunology. https://doi.org/10.4049/jimmunol.2000898