November 19, 2020

SARS-CoV-2 Viral Load on Admission Is Associated with 30-Day Mortality.

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics

• In a retrospective study of 181 patients admitted to UW Medicine hospitals, patients with a high SARS-CoV-2 viral load (Cycle threshold < 22) upon hospital admission had a 4.2-fold increase in odds of 30-day mortality. Meanwhile, those who were IgG seropositive had non-significantly lower odds of mortality (OR 0.43, 95% CI: 0.15-1.26). The authors suggest both virologic and serologic testing could serve as biomarkers for disease course.

Bryan et al. (Nov 3, 2020). SARS-CoV-2 Viral Load on Admission Is Associated with 30-Day Mortality. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofaa535