November 24, 2020

Stable Neutralizing Antibody Levels Six Months after Mild and Severe COVID-19 Episode

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

Pre-print, not peer reviewed] Longitudinal analysis of 210 Spanish patients followed for up to 242 days showed that individuals with mild or asymptomatic SARS-CoV-2 infection experienced a negligible decay in neutralizing antibody activity that persisted for six months after symptom onset, while hospitalized individuals showed an initial rapid decline in neutralizing titers that significantly slowed down after day 80. Despite this rapid decline, neutralizing titers among hospitalized patients remained higher at six months compared to titers among mild or asymptomatic individuals. 

Pradenas et al. (Nov 23, 2020). Stable Neutralizing Antibody Levels Six Months after Mild and Severe COVID-19 Episode. Pre-print downloaded Nov 24 from https://doi.org/10.1101/2020.11.22.389056