Alliance for Pandemic Preparedness

December 2, 2020

High Seroprevalence but Short‐lived Immune Response to SARS‐CoV‐2 Infection in Paris

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Serological testing among 1847 active workers in France showed declining antibody responses to SARS‐CoV‐2 4-8 weeks after the first sampling. Overall, 11% of workers were positive for IgG against SARS-CoV-2-specific proteins and 9.5% had evidence of viral neutralization. Among these, 21% were asymptomatic. In sera obtained 4–8 weeks after the first sampling, anti‐N and anti‐S IgG titers and neutralization activity declined by 31%, 17% and 53%, respectively. [EDITORIAL NOTE: This manuscript was previously summarized as a pre-print on Oct 28].

Anna et al. (Dec 1, 2020). High Seroprevalence but Short‐lived Immune Response to SARS‐CoV‐2 Infection in Paris. European Journal of Immunology. https://doi.org/10.1002/eji.202049058