Alliance for Pandemic Preparedness
December 2, 2020
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
Category: Article Summary
Topic: Testing and Treatment
Keywords (Tags): treatment
In a randomized trial of 11,330 adult inpatients with COVID-19 from 30 countries, with 2750 assigned to remdesivir, 954 to hydroxychloroquine, 1411 to lopinavir (without interferon), 2063 to interferon (including 651 to interferon plus lopinavir), and 4088 to no trial drug, all trial drugs had little or no effect on overall mortality, initiation of ventilation, and duration of hospital stay. [EDITORIAL NOTE: This manuscript was previously summarized as a pre-print on Oct 16].
WHO Solidarity Trial Consortium (Dec 2, 2020). Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results. The New England Journal of Medicine.