December 30, 2020

Prior SARS-CoV-2 Infection Is Associated with Protection against Symptomatic Reinfection

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

In a retrospective cohort study of healthcare workers (HCW) (n=17,126) in the UK, HCW without confirmed SARS-CoV-2 infection (negative PCR and serology) during the first wave experienced higher rates of symptomatic testing and PCR test positivity rates in the second wave 6 months later than HCW with confirmed SARS-CoV-2 infection during the first wave. Only 12.3% of HCW with previous infection presented for symptomatic testing, compared to 20.8% of HCW without previous infection. No positive PCR tests were returned among HCW with previous infection, whereas HCW with no previous infection had a 13.7% test positivity rate.

Hanrath et al. (Dec 26, 2020). Prior SARS-CoV-2 Infection Is Associated with Protection against Symptomatic Reinfection. Journal of Infection. https://doi.org/10.1016/j.jinf.2020.12.023