Alliance for Pandemic Preparedness

January 5, 2021

Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review

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A systematic review and meta-analysis showed declining COVID-19 vaccine acceptance, from >70% in March to <50% in October. In an analysis of data from 126 studies and surveys, drivers of decline  in vaccine acceptance included perceived risk, concerns over vaccine safety and effectiveness, doctors’ recommendations, and inoculation history. In assessing the impact of survey design, responses in surveys with more options (e.g., very likely/somewhat likely/neutral/somewhat unlikely/very unlikely, definitely/probably/probably not/definitely not) were more spread out compared to when fewer options were provided (e.g., yes/no/not sure or don’t know), which resulted in seemingly lower percentages of affirmative answers. Surveys that included different timings for vaccination showed hesitancy in getting first generation vaccines.

Lin et al. (Dec 30, 2020). Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review. Vaccines. https://doi.org/10.3390/vaccines9010016