Alliance for Pandemic Preparedness

January 6, 2021

Estimation of US SARS-CoV-2 Infections, Symptomatic Infections, Hospitalizations, and Deaths Using Seroprevalence Surveys

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A cross-sectional study using data from both public health surveillance records of reported COVID-19 cases and seroprevalence surveys found that an estimated 46,910,006 SARS-CoV-2 infections, 28,122,752 symptomatic infections, 956,174 hospitalizations, and 304,915 deaths occurred in the US through November 15, 2020. The authors note that 14% of the US population was infected with SARS-CoV-2 by mid-November, and SARS-CoV-2 disease burden may be much larger than reported COVID-19 cases due to underreporting. 

Angulo et al. (Jan 5, 2021). Estimation of US SARS-CoV-2 Infections, Symptomatic Infections, Hospitalizations, and Deaths Using Seroprevalence Surveys. JAMA Network Open. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2774584