January 6, 2021

Optimizing Vaccine Allocation for COVID-19 Vaccines Critical Role of Single-Dose Vaccination

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): vaccines

[Pre-print, not-peer reviewed] Utilizing an age-stratified mathematical model, a study of vaccine allocation strategy suggested that maintaining current social distancing interventions and speedy vaccine deployment were important, and the optimal allocation of vaccine depends on the single-dose efficacy (SDE). If SDE is high, single-dose vaccination would be the optimal use of vaccine under most scenarios considered and could prevent up to 48% more deaths than a strategy allocating vaccine to the high-risk (older age groups) first. If SDE is low or medium, mixed vaccination campaigns with one and two doses of vaccine are best. 

Matrajt et al. (Jan 5, 2021). Optimizing Vaccine Allocation for COVID-19 Vaccines Critical Role of Single-Dose Vaccination. Pre-print downloaded Jan 6 from https://doi.org/10.1101/2020.12.31.20249099