Alliance for Pandemic Preparedness

January 20, 2021

Follow‐up of SARS‐CoV‐2 Positive Subgroup from the Asymptomatic Novel CORonavirus INfection (ACORN) Study

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22% of asymptomatic participants with positive SARS-CoV-2 nasopharyngeal swabs developed symptoms within 14 days, according to results from the Asymptomatic novel CORonavirus iNfection (ACORN). Symptoms developed in 19 out of 86 participants a median of 6 days after the initial positive test result, the most frequently reported of which were fatigue or muscle aches (11%), headache (9%), fever (6%), and shortness of breath (6%). Of the 78 participants who submitted a nasopharyngeal swab for repeat RT‐PCR testing, 17 (22%) remained positive at Day 14, and 4 continued to test positive at Day 28.

Meyers et al. (Jan 19, 2021). Follow‐up of SARS‐CoV‐2 Positive Subgroup from the Asymptomatic Novel CORonavirus INfection (ACORN) Study. Journal of Medical Virology. https://doi.org/10.1002/jmv.26810