Alliance for Pandemic Preparedness

January 26, 2021

Using Non-Pharmaceutical Interventions and High Isolation of Asymptomatic Carriers to Contain the Spread of SARS-CoV-2 in Nursing Homes

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[Pre-print, not peer-reviewed] A pandemic influenza model with COVID-19 parameters applied to a nursing home setting showed that the attack rate was more sensitive to identification and isolation of asymptomatic cases than implementation of non-pharmaceutical interventions (NPIs). Varying NPI levels from baseline to rigorous measures had no significant effect on attack rate in a scenario without isolation of asymptomatic cases, whereas NPI scenarios showed large reductions in attack rate  when used in conjunction with 90% isolation (up to 43% reduction). Hospitalizations, ICU admissions, and mortality rate were all reduced as the attack rate fell.

Schmidt et al. (Jan 25, 2021). Using Non-Pharmaceutical Interventions and High Isolation of Asymptomatic Carriers to Contain the Spread of SARS-CoV-2 in Nursing Homes. Pre-print downloaded Jan 26 from https://doi.org/10.1101/2021.01.22.21249308