Alliance for Pandemic Preparedness

January 27, 2021

Trends Regional Variation and Clinical Characteristics of COVID-19 Vaccine Recipients a Retrospective Cohort Study in 23.4 Million Patients Using OpenSAFELY

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[Pre-print, not per-reviewed] A retrospective cohort study of electronic health record data from the National Health System in England from 23.4 million patients using the OpenSAFELY-TPP platform found that between December 8 and January 13, 2021, a total of 961,580 people received a COVID-19 vaccine. Of 1,160,062 patients aged 80 or over and not living in a care home, 41% had been vaccinated. Within this group, there were substantial differences in vaccination by ethnicity (white 43% vaccinated, Black 21%) and across rankings of deprivation (least deprived 45%, most deprived 38%). In the 70-79 age cohort, 4% had been vaccinated. Among those age 65-70 who were care home residents the vaccine coverage was 33%. Of all those vaccinated, 18% (169,472 persons) had received a second dose. 

MacKenna et al. (Jan 26, 2021). Trends Regional Variation and Clinical Characteristics of COVID-19 Vaccine Recipients a Retrospective Cohort Study in 23.4 Million Patients Using OpenSAFELY. Pre-print downloaded January 27 from https://doi.org/10.1101/2021.01.25.21250356