February 8, 2021

Rapid Electrochemical Detection of Coronavirus SARS-CoV-2Rapid Electrochemical Detection of Coronavirus SARS-CoV-2

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): testing

A study describing an electrochemical biosensor based on multiplex rolling circle amplification (RCA, in which a short DNA or RNA primer is amplified to make a long single strand) to detect the N and S genes of the SARS-CoV-2 virus showed that the assay could detect as few as 1 copy/microliter of the genes in under 2 hours. The sensor was evaluated with 106 clinical samples (41 from SARS-CoV-2 positive individuals and 9 from other respiratory viruses) and showed 100% concordance with qRT-PCR. 

Chaibun et al. (Dec 5, 2021). Rapid Electrochemical Detection of Coronavirus SARS-CoV-2. Nature Communications. https://doi.org/10.1038/s41467-021-21121-7