Alliance for Pandemic Preparedness

March 2, 2021

REACT-2 Round 5 Increasing Prevalence of SARS-CoV-2 Antibodies Demonstrate Impact of the Second Wave and of Vaccine Roll-out in England

Category:

Topic:

Keywords (Tags): ,

  • [Pre-print, not peer-reviewed] A nationwide cross-sectional study in the England (n=172,000) conducted between January 26 to February 8, 2021 found that the SARS-CoV-2-specific antibody seroprevalence representative of the national population was 14% overall. This figure included seroprevalence due to both immunization and infection. Seroprevalence in unvaccinated people was highest in London and among members of racial and ethnic minority populations. Vaccine confidence was at 92%, though lower among young people and those of Black ethnicity. Seroprevalence was at 84% among those receiving a single dose of the Pfizer vaccine and under 60 years of age, with a decreasing trend in older age groups. Those with confirmed or suspected prior COVID-19 had 90% seroprevalence across age groups.

Ward et al. (Mar 1, 2021). REACT-2 Round 5 Increasing Prevalence of SARS-CoV-2 Antibodies Demonstrate Impact of the Second Wave and of Vaccine Roll-out in England. Pre-print downloaded Mar 2 from https://doi.org/10.1101/2021.02.26.21252512